![]() The ePlex panel (16) has been proven to be a highly sensitive and specific multiplex assay for respiratory pathogen detection. It is an FDA approved assay that simultaneous detects 19 viruses (influenza A virus influenza A H1 virus influenza A 2009 H1 virus influenza A H3 virus influenza B virus adenovirus coronaviruses human rhinovirus/enterovirus human metapneumovirus parainfluenza viruses 1, 2, 3, and 4 and respiratory syncytial virus ) and 2 bacteria (Mycoplasma pneumoniae and Chlamydia pneumoniae). A translation of this abstract in Farsi is available in the supplement. © RSNA, 2020 Online supplemental material is available for this article. Conclusion Radiologists in China and in the United States distinguished coronavirus disease 2019 from viral pneumonia at chest CT with moderate to high accuracy. 001), but it was less likely to have a central and peripheral distribution (14% vs 35%, P <. 001), and vascular thickening (59% vs 22%, P <. Compared with non-COVID-19 pneumonia, COVID-19 pneumonia was more likely to have a peripheral distribution (80% vs 57%, P <. The corresponding specificities of the same readers were 100%, 93%, 7%, 100%, 93%, 93%, and 100%, respectively. In the randomly selected sample ( n = 58), the sensitivities of three radiologists from China and four radiologists from the United States were 80%, 67%, 97%, 93%, 83%, 73%, and 70%, respectively. Results For all chest CT scans ( n = 424), the accuracy of the three radiologists from China in differentiating COVID-19 from non-COVID-19 viral pneumonia was 83% (350 of 424), 80% (338 of 424), and 60% (255 of 424). Different CT features were recorded and compared between the two groups. A sample of 58 age-matched patients was randomly selected and evaluated by four radiologists from the United States in a similar fashion. Three radiologists from China reviewed all chest CT scans ( n = 424) blinded to RT-PCR findings to differentiate COVID-19 from viral pneumonia. Two hundred five patients with positive respiratory pathogen panel results for viral pneumonia and CT findings consistent with or highly suspicious for pneumonia, according to original radiologic interpretation within 7 days of each other, were identified from Rhode Island Hospital in Providence, RI. Materials and Methods In this study, 219 patients with positive COVID-19, as determined with reverse-transcription polymerase chain reaction (RT-PCR) and abnormal chest CT findings, were retrospectively identified from seven Chinese hospitals in Hunan Province, China, from January 6 to February 20, 2020. Purpose To assess the performance of radiologists in the United States and China in differentiating COVID-19 from viral pneumonia at chest CT. Background Despite its high sensitivity in diagnosing coronavirus disease 2019 (COVID-19) in a screening population, the chest CT appearance of COVID-19 pneumonia is thought to be nonspecific. ![]()
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